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Correction to: _Nature_ https://doi.org/10.1038/s41586-018-0238-4Published online 20 June 2018 In this Letter, the isotopologue used to demonstrate hydrogen atom abstraction from CTP was
incorrectly identified as 2′,3′,4′,5′,5-deutero-CTP, whereas the isotopologue we used was 3′,4′,5′,5-deutero-CTP. (Boldface indicates where changes were made.) In the main text, the sentence
“Incubation of rVIP with SAM and CTP deuterated at the 2′, 3′, 4′, 5′ and 5 positions (deuCTP), increased the −_m_/_z_ of 5ʹ-dA from 250.1 to 251.1, consistent with the transfer of one
deuterium from deuCTP to 5ʹ-dA.” should have read “Incubation of rVIP with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP) increased the −_m_/_z_ of 5ʹ-dA from 250.1 to
251.1, consistent with the transfer of one deuterium from deuCTP to 5ʹ-dA.”. In the Extended Data Fig. 3 legend the sentence “When rVIP was incubated with SAM and CTP deuterated at the 2′,
3′, 4′, 5′ and 5 positions (deuCTP), the −_m_/_z_ of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from deuCTP to 5′-dA•.” should have read: “When rVIP
was incubated with SAM and CTP deuterated at the 3′, 4′, 5′ and 5 positions (deuCTP), the −_m_/_z_ of 5′-dA increased from 250.1 to 251.1, consistent with the transfer of one deuterium from
deuCTP to 5′-dA•.” Similarly, the name of the isotopologue appeared incorrectly in the Supplementary Information. In the Supplementary Information section ‘Hydrogen atom abstraction
specificity’ the sentence “Reactions of 100 μL total volume contained 100 μM rVIP, 50 mM HEPES pH 7.5, 150 mM KCl, 1 mM SAM, and 1 mM deuterium-labeled CTP (site-specifically labeled CTP
contains deuterium at the following positioN; (2'-2H, 3'-2H, 4'-2H, or 5'-2H2-CTP)).” should have read: "Reactions of 100 μL total volume contained 100 μM rVIP, 50
mM HEPES pH 7.5, 150 mM KCl, 1 mM SAM, and 1 mM deuterium-labelled CTP (site-specifically labelled CTP contains deuterium at the following positions:
3'-2H,4'-2H,5'-2H2,5-2H-CTP or 2'-2H-CTP,3'-2H-CTP,4'-2H-CTP or 5'-2H2-CTP). In the Supplementary Information section ‘2'-deoxy-CTP vs deutero-CTP
substrate specificity assays’ the sentence “Reactions of 100 μL total volume contained 100 μM rVIP, 50 mM HEPES pH 7.5, 150 mM KCl, 1 mM SAM, 1 mM deutero-CTP (2'-2H, 3'-2H,
4'-2H, 5'-2H2, AND 5-2H –CTP), and unlabeled 1 mM 2'-deoxy-CTP.” should have read: “Reactions of 100 μL total volume contained 100 μM rVIP, 50 mM HEPES pH 7.5, 150 mM KCl, 1
mM SAM, 1 mM deutero-CTP (3'-2H,4'-2H,5'-2H2,5-2H-CTP), and unlabelled 1 mM 2'-deoxy-CTP.” These errors have been corrected online. AUTHOR INFORMATION Author notes *
These authors contributed equally: Anthony S. Gizzi, Tyler L. Grove AUTHORS AND AFFILIATIONS * Department of Biochemistry, Albert Einstein College of Medicine, Bronx, NY, USA Anthony S.
Gizzi, Tyler L. Grove, Scott J. Garforth, Quan Du, Sean M. Cahill, Natalya G. Dulyaninova, Anne R. Bresnick & Steven C. Almo * Department of Biochemistry and Molecular Biology, The
Pennsylvania State University, University Park, PA, USA Jamie J. Arnold, Joyce Jose & Craig E. Cameron * Department of Microbiology and Immunology, Albert Einstein College of Medicine,
Bronx, NY, USA Rohit K. Jangra & Kartik Chandran * Institute for Protein Innovation, Boston, MA, USA James D. Love & Steven C. Almo Authors * Anthony S. Gizzi View author
publications You can also search for this author inPubMed Google Scholar * Tyler L. Grove View author publications You can also search for this author inPubMed Google Scholar * Jamie J.
Arnold View author publications You can also search for this author inPubMed Google Scholar * Joyce Jose View author publications You can also search for this author inPubMed Google Scholar
* Rohit K. Jangra View author publications You can also search for this author inPubMed Google Scholar * Scott J. Garforth View author publications You can also search for this author
inPubMed Google Scholar * Quan Du View author publications You can also search for this author inPubMed Google Scholar * Sean M. Cahill View author publications You can also search for this
author inPubMed Google Scholar * Natalya G. Dulyaninova View author publications You can also search for this author inPubMed Google Scholar * James D. Love View author publications You can
also search for this author inPubMed Google Scholar * Kartik Chandran View author publications You can also search for this author inPubMed Google Scholar * Anne R. Bresnick View author
publications You can also search for this author inPubMed Google Scholar * Craig E. Cameron View author publications You can also search for this author inPubMed Google Scholar * Steven C.
Almo View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Steven C. Almo. RIGHTS AND PERMISSIONS Reprints and
permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Gizzi, A.S., Grove, T.L., Arnold, J.J. _et al._ Author Correction: A naturally occurring antiviral ribonucleotide encoded by the human
genome. _Nature_ 583, E15 (2020). https://doi.org/10.1038/s41586-020-2322-9 Download citation * Published: 16 June 2020 * Issue Date: 02 July 2020 * DOI:
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