Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease

Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease

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Download PDF Author Correction Open access Published: 14 August 2024 Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease Nadezda Podvalnaya1,2 na1, Alfred W. Bronkhorst  ORCID: orcid.org/0000-0001-6402-574X1 na1, Raffael Lichtenberger3,4, Svenja Hellmann1, Emily Nischwitz2,5, Torben Falk  ORCID: orcid.org/0000-0001-9737-70553,4, Emil Karaulanov6, Falk Butter  ORCID: orcid.org/0000-0002-7197-72794 nAff8, Sebastian Falk  ORCID: orcid.org/0000-0001-7848-46213,4 & …René F. Ketting  ORCID: orcid.org/0000-0001-6161-56211,7 Show authors Nature volume 632, page E31 (2024)Cite this article  1337 Accesses 1 Altmetric Metrics details Subjects Germline developmentNon-coding RNAsRNARNAiX-ray crystallography The Original Article was published on 27 September 2023Correction to: Nature https://doi.org/10.1038/s41586-023-06588-2 Published online 27 September 2023After our manuscript was published, we were alerted by an anonymous reader that four elemental ions modeled in the crystal structure of the TOFU-6eTUDOR/TOFU-1pep complex are most likely incorrect. Moreover, the density of TOFU-1pep was weak, probably due to low occupancy. To address those issues, we have now determined the structure from a different crystal, diffracting to 2.2 Å, showing clearer density for TOFU-1pep. Also, the erroneously modeled elemental ions were corrected. A new version of Supplementary Data has been uploaded containing an updated version of Extended Data Table 1 | Data collection and refinement statistics.In the main text of the manuscript, we now changed the following sentences:The original sentence “We determined the crystal structure of the TOFU-6eTUDOR–TOFU-1pep complex at a resolution of 1.7 Å (Fig. 5c and Extended Data Table 1)” now reads “We determined the crystal structure of the TOFU-6eTUDOR–TOFU-1pep complex at a resolution of 2.2 Å (Fig. 5c and Extended Data Table 1)”.In the Methods section, the sentence “The refined model has a clashscore of 5.06 and 98.54% of the residues fall into Ramachandran-favoured and 1.46% into Ramachandran-allowed regions” has been updated to “The refined model has a clashscore of 1.17 and 98.56% of the residues fall into Ramachandran-favoured and 1.44% into Ramachandran-allowed regions”.In the Methods and Data availability sections, the sentence “Coordinates and structure factors of the TOFU-6eTUDOR–TOFU-1pep complex structure have been deposited at the PDB (8BY5)” now reads “Coordinates and structure factors of the TOFU-6eTUDOR–TOFU-1pep complex structure have been deposited at the PDB (9G6Z)”.None of the manuscript’s interpretations are affected by this correction. These changes have been made to the HTML and PDF versions of the article. Author informationAuthor notes Falk Butter Present address: Institute of Molecular Virology and Cell Biology, Friedrich Loeffler Institute, Greifswald, GermanyThese authors contributed equally: Nadezda Podvalnaya, Alfred W. BronkhorstAuthors and Affiliations Biology of Non-coding RNA group, Institute of Molecular Biology, Mainz, Germany Nadezda Podvalnaya, Alfred W. Bronkhorst, Svenja Hellmann & René F. Ketting International PhD Programme on Gene Regulation, Epigenetics & Genome Stability, Mainz, Germany Nadezda Podvalnaya & Emily Nischwitz Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria Raffael Lichtenberger, Torben Falk & Sebastian Falk Department of Structural and Computational Biology, Center for Molecular Biology, University of Vienna, Vienna, Austria Raffael Lichtenberger, Torben Falk, Falk Butter & Sebastian Falk Quantitative Proteomics group, Institute of Molecular Biology, Mainz, Germany Emily Nischwitz Bioinformatics Core Facility, Institute of Molecular Biology, Mainz, Germany Emil Karaulanov Institute of Developmental Biology and Neurobiology, Johannes Gutenberg University, Mainz, Germany René F. KettingAuthorsNadezda PodvalnayaView author publications You can also search for this author inPubMed Google ScholarAlfred W. BronkhorstView author publications You can also search for this author inPubMed Google ScholarRaffael LichtenbergerView author publications You can also search for this author inPubMed Google ScholarSvenja HellmannView author publications You can also search for this author inPubMed Google ScholarEmily NischwitzView author publications You can also search for this author inPubMed Google ScholarTorben FalkView author publications You can also search for this author inPubMed Google ScholarEmil KaraulanovView author publications You can also search for this author inPubMed Google ScholarFalk ButterView author publications You can also search for this author inPubMed Google ScholarSebastian FalkView author publications You can also search for this author inPubMed Google ScholarRené F. KettingView author publications You can also search for this author inPubMed Google ScholarCorresponding authors Correspondence to Sebastian Falk or René F. Ketting.Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Reprints and permissionsAbout this articleCite this article Podvalnaya, N., Bronkhorst, A.W., Lichtenberger, R. et al. Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease. Nature 632, E31 (2024). https://doi.org/10.1038/s41586-024-07938-4 Download citationPublished: 14 August 2024Issue Date: 29 August 2024DOI: https://doi.org/10.1038/s41586-024-07938-4Share this article Anyone you share the following link with will be able to read this content:Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

Download PDF Author Correction Open access Published: 14 August 2024 Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease Nadezda Podvalnaya1,2 na1, Alfred W.


Bronkhorst  ORCID: orcid.org/0000-0001-6402-574X1 na1, Raffael Lichtenberger3,4, Svenja Hellmann1, Emily Nischwitz2,5, Torben Falk  ORCID: orcid.org/0000-0001-9737-70553,4, Emil Karaulanov6,


Falk Butter  ORCID: orcid.org/0000-0002-7197-72794 nAff8, Sebastian Falk  ORCID: orcid.org/0000-0001-7848-46213,4 & …René F. Ketting  ORCID: orcid.org/0000-0001-6161-56211,7 Show authors


Nature volume 632, page E31 (2024)Cite this article


1337 Accesses


1 Altmetric


Metrics details


Subjects Germline developmentNon-coding RNAsRNARNAiX-ray crystallography The Original Article was published on 27 September 2023


Correction to: Nature https://doi.org/10.1038/s41586-023-06588-2 Published online 27 September 2023


After our manuscript was published, we were alerted by an anonymous reader that four elemental ions modeled in the crystal structure of the TOFU-6eTUDOR/TOFU-1pep complex are most likely


incorrect. Moreover, the density of TOFU-1pep was weak, probably due to low occupancy. To address those issues, we have now determined the structure from a different crystal, diffracting to


2.2 Å, showing clearer density for TOFU-1pep. Also, the erroneously modeled elemental ions were corrected. A new version of Supplementary Data has been uploaded containing an updated version


of Extended Data Table 1 | Data collection and refinement statistics.


In the main text of the manuscript, we now changed the following sentences:


The original sentence “We determined the crystal structure of the TOFU-6eTUDOR–TOFU-1pep complex at a resolution of 1.7 Å (Fig. 5c and Extended Data Table 1)” now reads “We determined the


crystal structure of the TOFU-6eTUDOR–TOFU-1pep complex at a resolution of 2.2 Å (Fig. 5c and Extended Data Table 1)”.


In the Methods section, the sentence “The refined model has a clashscore of 5.06 and 98.54% of the residues fall into Ramachandran-favoured and 1.46% into Ramachandran-allowed regions” has


been updated to “The refined model has a clashscore of 1.17 and 98.56% of the residues fall into Ramachandran-favoured and 1.44% into Ramachandran-allowed regions”.


In the Methods and Data availability sections, the sentence “Coordinates and structure factors of the TOFU-6eTUDOR–TOFU-1pep complex structure have been deposited at the PDB (8BY5)” now


reads “Coordinates and structure factors of the TOFU-6eTUDOR–TOFU-1pep complex structure have been deposited at the PDB (9G6Z)”.


None of the manuscript’s interpretations are affected by this correction. These changes have been made to the HTML and PDF versions of the article.


Author informationAuthor notes Falk Butter


Present address: Institute of Molecular Virology and Cell Biology, Friedrich Loeffler Institute, Greifswald, Germany


These authors contributed equally: Nadezda Podvalnaya, Alfred W. Bronkhorst


Authors and Affiliations Biology of Non-coding RNA group, Institute of Molecular Biology, Mainz, Germany


Nadezda Podvalnaya, Alfred W. Bronkhorst, Svenja Hellmann & René F. Ketting


International PhD Programme on Gene Regulation, Epigenetics & Genome Stability, Mainz, Germany


Nadezda Podvalnaya & Emily Nischwitz


Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, Austria


Raffael Lichtenberger, Torben Falk & Sebastian Falk


Department of Structural and Computational Biology, Center for Molecular Biology, University of Vienna, Vienna, Austria


Raffael Lichtenberger, Torben Falk, Falk Butter & Sebastian Falk


Quantitative Proteomics group, Institute of Molecular Biology, Mainz, Germany


Emily Nischwitz


Bioinformatics Core Facility, Institute of Molecular Biology, Mainz, Germany


Emil Karaulanov


Institute of Developmental Biology and Neurobiology, Johannes Gutenberg University, Mainz, Germany


René F. Ketting


AuthorsNadezda PodvalnayaView author publications You can also search for this author inPubMed Google Scholar


Alfred W. BronkhorstView author publications You can also search for this author inPubMed Google Scholar


Raffael LichtenbergerView author publications You can also search for this author inPubMed Google Scholar


Svenja HellmannView author publications You can also search for this author inPubMed Google Scholar


Emily NischwitzView author publications You can also search for this author inPubMed Google Scholar


Torben FalkView author publications You can also search for this author inPubMed Google Scholar


Emil KaraulanovView author publications You can also search for this author inPubMed Google Scholar


Falk ButterView author publications You can also search for this author inPubMed Google Scholar


Sebastian FalkView author publications You can also search for this author inPubMed Google Scholar


René F. KettingView author publications You can also search for this author inPubMed Google Scholar


Corresponding authors Correspondence to Sebastian Falk or René F. Ketting.

Rights and permissions


Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or


format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or


other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in


the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the


copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.


Reprints and permissions


About this articleCite this article Podvalnaya, N., Bronkhorst, A.W., Lichtenberger, R. et al. Author Correction: piRNA processing by a trimeric Schlafen-domain nuclease. Nature 632, E31


(2024). https://doi.org/10.1038/s41586-024-07938-4


Download citation


Published: 14 August 2024


Issue Date: 29 August 2024


DOI: https://doi.org/10.1038/s41586-024-07938-4


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