By using genetic admixture in the multi-omic analysis of postmortem brains from Black Americans, we show that genetic ancestry influences gene expression in the brain. Notably, we find

enrichment of ancestry-associated genes for immune response and vascular function, but not neuronal function. Our findings have potential implications for stroke, Parkinson’s disease and

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jurisdictional claims in published maps and institutional affiliations. THIS IS A SUMMARY OF: Benjamin, K. J. M. et al. Analysis of gene expression in the postmortem brain of neurotypical

Black Americans reveals contributions of genetic ancestry. _Nat. Neurosci_. https://doi.org/10.1038/s41593-024-01636-0 (2024). RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS

ARTICLE CITE THIS ARTICLE Genetic ancestry contributes to gene expression in the brain. _Nat Neurosci_ 27, 1042–1043 (2024). https://doi.org/10.1038/s41593-024-01645-z Download citation *

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