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Obesity is commonly associated with leptin resistance. Inhibition of HDAC6 in adipose tissue of mice with diet-induced obesity produces a protein factor that augments leptin’s ability to
reduce feeding and body weight, and improve glucose tolerance. HDAC6 inhibition acts as a novel treatment for obesity by ameliorating leptin resistance. Access through your institution Buy
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checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Bray, G. A. et al. _Endocr. Rev._ 39, 79–132
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INFORMATION AUTHORS AND AFFILIATIONS * Department of Medicine, Division of Endocrinology, Diabetes and Metabolism, Johns Hopkins University School of Medicine, Baltimore, MD, USA Rexford S.
Ahima Authors * Rexford S. Ahima View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR Correspondence to Rexford S. Ahima. ETHICS
DECLARATIONS COMPETING INTERESTS The author declares no competing interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Ahima, R.S. HDAC6 inhibition
overcomes leptin resistance in obesity. _Nat Metab_ 4, 11–12 (2022). https://doi.org/10.1038/s42255-021-00500-w Download citation * Published: 17 January 2022 * Issue Date: January 2022 *
DOI: https://doi.org/10.1038/s42255-021-00500-w SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is
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