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ABSTRACT Spinal cord seizures are infrequently reported. They have been associated with intravenous dye placement, transverse myelitis and multiple sclerosis, but never with traumatic spinal
cord injury (SCI). We report the case of a 48-year-old SCI male with complete C6 quadriplegia, and apparent spinal cord seizures. These seizures were characterised by myoclonus simplex
activity involving the upper extremities only. The lower extremities were spared. The patient was conscious throughout the myoclonic activity and an electroencephalogram of the brain
obtained during an event revealed no cortical epiliptiform activity. The seizures lasted approximately 30 seconds to a few minutes, and an acute increase in blood pressure and a decrease in
pulse generally occurred 30 to 60 seconds prior to the event. Previously reported spinal cord seizures in multiple sclerosis were frequently treated with carbamazepine. In this case
successful treatment was with diazepam. Spinal cord seizures may present in those with traumatic SCI. Benzodiaze-pines may be useful in the treatment of spinal cord seizures. SIMILAR CONTENT
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references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Virginia Spinal Cord Injury System, University of Virginia Health Sciences Center, Charlottesville, 22908, Virginia, USA J M
Meythaler, S M Tuel & L L Cross Authors * J M Meythaler View author publications You can also search for this author inPubMed Google Scholar * S M Tuel View author publications You can
also search for this author inPubMed Google Scholar * L L Cross View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and
permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Meythaler, J., Tuel, S. & Cross, L. Spinal cord seizures: a possible cause of isolated myoclonic activity in traumatic spinal cord
injury. _Spinal Cord_ 29, 557–560 (1991). https://doi.org/10.1038/sc.1991.81 Download citation * Issue Date: 01 October 1991 * DOI: https://doi.org/10.1038/sc.1991.81 SHARE THIS ARTICLE
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by the Springer Nature SharedIt content-sharing initiative KEYWORDS * Spinal cord injury * Seizures * Myoclonus * Benzodiazepines * Autonomic dysreflexia * Spasticity