Play all audios:
A selection of abstracts of clinically relevant papers from other journals. The abstracts on this page have been chosen and edited by JOHN R. RADFORD. ABSTRACT The Colgate toothpastes
containing 8% arginine 'lead(s) to a shift in the salivary microbiome composition towards a healthy ecology'. MAIN Koopman JE, Hoogenkamp MA _et al_. _Arch Oral Biol_ 2016; 73:
79–87 Prebiotics foster human health by working with specific microbes. But can arginine be metabolised by oral bacteria such that the pH of the oral cavity is increased? Colgate Sensitive
Pro-Relief Toothpaste is one of a range of toothpastes (Extra Sensitive and Repair and Prevent, to name just two) that contain 8% arginine. This group of Colgate toothpastes is not to be
confused with Colgate Maximum Cavity Protection with Sugar Acid Neutraliser which contains 1.5% arginine; clinical trials on the efficacy of this latter toothpaste have been the subject of
controversy (see The tribulations of toothpaste: Unethical arginine dentifrice research. _Br Dent J_ 2015; 219: 567–569). In this pilot study published in _Arch Oral Biol_, nine subjects
used a toothpaste containing 8% arginine for eight weeks. Saliva was collected to determine arginolytic and sucrose metabolic activities. Although the investigators did not recruit a control
group and the number of subjects were small, the following observations were made: 1) the arginolytic potential of saliva increased, whereas the sucrose metabolism in saliva decreased; 2)
this was reversed during the wash-out period; 3) there was no change in the plaque microbiome, in contrast to the saliva microbiome, where there was an increase in the composition of the
genus _Veillonella_. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Changes in the oral ecosystem induced by the use of 8% arginine toothpaste. _Br Dent
J_ 221, 772 (2016). https://doi.org/10.1038/sj.bdj.2016.946 Download citation * Published: 16 December 2016 * Issue Date: 16 December 2016 * DOI: https://doi.org/10.1038/sj.bdj.2016.946
SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to
clipboard Provided by the Springer Nature SharedIt content-sharing initiative