The cover depicts conidiophores of the fungus _Aspergillus nidulans_ carrying a fungal artificial chromosome (FAC), imaged by a scanning electron microscope and colored artificially.

Filamentous fungi are prolific producers of secondary metabolites, and the combination of FAC technology with metabolomic scoring enables the high-throughput linkage of these metabolites

with their biosynthetic gene clusters. Cover design by Erin Dewalt, based on an image from Eric W. Roth. Article, p895