Play all audios:
VOL: 98, ISSUE: 46, PAGE NO: 30 EPIDEMIOLOGY EPIDEMIOLOGY Rheumatoid arthritis is the most common form of chronic inflammatory joint disease. It is a systemic disease but with most notable
effect on synovial joints. The prevalence of RA is 1.16% in women and 0.44% in men in the UK. The disease starts most commonly in the age range 30-60 years. AETIOLOGY There is no known cause
for RA but it is thought to be an autoimmune disease in which the body's immune system mistakenly attacks its own tissue. Development of this autoimmunity is thought to be initiated by
microbial infection, possibly viruses in genetically susceptible people. There are no specific risk factors for RA. SIGNS AND SYMPTOMS - In the majority of patients the onset is insidious,
with joint pain, stiffness and symmetrical swelling of peripheral joints. - Morning stiffness lasting at least one hour is a feature of RA. - Other symptoms include weakness, fatigue, fever
and weight loss. DIAGNOSIS - A full health history should be taken and a physical examination performed. - Laboratory tests - levels of C-reactive protein level and erythrocyte sedimentation
rate (ESR) are usually elevated. White blood cell count can be raised in RA. Rheumatoid factors (RF) are usually found in the blood and in synovial fluid. - Radiographic findings - to
detect RA changes in order to determine potential usefulness of drugs or surgery. These may show soft tissue swelling, bone demineralisation, cartilage erosion, joint space narrowing and
bony cysts. - Synovial fluid analysis - to measure viscosity which is usually lowered in RA. White blood cells are present in RA, and a mucin clot test is performed. TREATMENT - Drug therapy
- non-steroidal anti-inflammatory drugs (NSAIDS) and disease modifying anti-rheumatic drugs (DMARDS). - Supportive - rest, splinting of affected joints and use of orthotic devices. -
Surgical - total joint replacements. NURSING IMPLICATIONS Assessment of pain, swelling, tenderness, limitation of movement, fatigue and joint deformities. Consider and discuss the
patients' ability to perform activities of daily living and coping with physical and functional losses. WEBSITES FURTHER READING Linton A, et al (2000)_Introductory Nursing Care of
Adults. Philadelphia: WB Saunders Company._