Play all audios:
Cells package proteins into vesicles for secretion to the extracellular milieu. A study has now identified an enzyme that modifies the packaging machinery to encapsulate unusually large
proteins, such as collagen. SEE ARTICLE p.495 Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access
through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink *
Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional
subscriptions * Read our FAQs * Contact customer support REFERENCES * Zanetti, G., Pahuja, K. B., Studer, S., Shim, S. & Schekman, R. _Nat. Cell. Biol_. 14, 20–28 (2012). Article CAS
Google Scholar * Jin, L. et al. _Nature_ 482, 495–500 (2012). Article ADS CAS Google Scholar * Stagg, S. M. et al. _Cell_ 134, 474–484 (2008). Article CAS Google Scholar * Fath, S.,
Mancias, J. D., Bi, X. & Goldberg, J. _Cell_ 129, 1325–1336 (2007). Article CAS Google Scholar * Komander, D. _Biochem. Soc. Trans._ 37, 937–953 (2009). Article CAS Google Scholar
* Saito, K. et al. _Cell_ 136, 891–902 (2009). Article CAS Google Scholar * Wilson, D. G. et al. _J. Cell Biol_. 193, 935–951 (2011). Google Scholar * De Matteis, M. A. & Luini, A.
_N. Engl. J. Med._ 365, 927–938 (2011). Article CAS Google Scholar Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * David J. Stephens is in the Cell Biology Laboratories,
School of Biochemistry, University of Bristol, Bristol BS8 1TD, UK, David J. Stephens Authors * David J. Stephens View author publications You can also search for this author inPubMed
Google Scholar CORRESPONDING AUTHOR Correspondence to David J. Stephens. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Stephens, D. Collagen secretion
explained. _Nature_ 482, 474–475 (2012). https://doi.org/10.1038/482474a Download citation * Published: 22 February 2012 * Issue Date: 23 February 2012 * DOI: https://doi.org/10.1038/482474a
SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy
to clipboard Provided by the Springer Nature SharedIt content-sharing initiative