Play all audios:
_In response to the questions posed in this scenario, the Office of Laboratory Animal Welfare (OLAW) offers the following guidance:_ The Office of Laboratory Animal Welfare (OLAW)
acknowledges the thoughtful advice of the commenters and supports the importance of research personnel receiving adequate training and education prior to conducting procedures on animals.
One of the commenters suggests reclassifying the mice that died into USDA Category E. Both the PHS Policy and the _Guide for the Care and Use of Laboratory Animals_ expect procedures that
may cause pain or distress to be performed with appropriate sedation, analgesia, or anesthesia, unless justified for scientific reasons1,2. Some IACUCs choose to monitor compliance with this
expectation by assigning USDA pain categories to non-regulated species, but this is not required. IACUCs may develop other methods to comply with the Policy and the _Guide_. Return to
Protocol Review REFERENCES * Public Health Service Policy on Humane Care and Use of Laboratory Animals, IV.C.1.b. (US Department of Health and Human Services, Bethesda, MD, 1986; revised
2015, NIH Publication No. 15-8013 http://grants.nih.gov/grants/olaw/references/phspol.htm). * Institute for Laboratory Animal Research. _Guide for the Care and Use of Laboratory Animals_ 8th
edn. p. 26 (National Academies Press, Washington, DC, 2011). Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Director OLAW, OER, OD, NIH, HHS, Patricia Brown Authors *
Patricia Brown View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE
Brown, P. Response to Protocol Review Scenario: A Word from OLAW. _Lab Anim_ 45, 356 (2016). https://doi.org/10.1038/laban.1123 Download citation * Published: 21 September 2016 * Issue Date:
October 2016 * DOI: https://doi.org/10.1038/laban.1123 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable
link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative