Computational neuroscience and neurology

Computational neuroscience and neurology

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Computer simulations of theoretical models provide a way to elucidate mechanisms underlying neurological disorders and drug actions. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Hodgkin, A.L. & Huxley, A.F. A quantitative description of membrane current and its application to conduction and excitation in nerve. _J. Physiol Lond._ 117, 500–544 (1952). Article  CAS  Google Scholar  * Cannon, S.C. & Corey, D.P. Loss of sodium channel inactivation by anemone toxin (ATX II) mimics the myotonic state in hyperkaliemic periodic paralysis. _J. Physiol._ 466, 501–520 (1993). CAS  PubMed  PubMed Central  Google Scholar  * Cannon, S.C., Brown, R.H. & Corey, D. Theoretical reconstruction of myotonia and paralysis caused by incomplete inactivation of sodium channels. _Biophys. J._ 65, 270–288 (1993). Article  CAS  Google Scholar  * Lytton, W.W. & Sejnowski, T.J. Computer model of ethosuximide's effect on a thalamic neuron. _Ann. Neurol._ 32, 131–139 (1992). Article  CAS  Google Scholar  * Vibert, J.-F., Pham, J., Pakdaman, K. & Azmy, N. XNBC: A simulation tool for neurobiologists. in _The Neurobiology of Computation_ (ed. Bower, J.) 346–352 (Kluwer Academic Pub., Boston, 1995). Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Faculté de Médecine Saint–Antoine, Université Pierre et Marie–Curie, 75571, Paris Cedex, 12, France Jean-Francois Vibert, Khashayar Pakdaman, Eric Boussard & Evyatar Av-Ron Authors * Jean-Francois Vibert View author publications You can also search for this author inPubMed Google Scholar * Khashayar Pakdaman View author publications You can also search for this author inPubMed Google Scholar * Eric Boussard View author publications You can also search for this author inPubMed Google Scholar * Evyatar Av-Ron View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Vibert, JF., Pakdaman, K., Boussard, E. _et al._ Computational neuroscience and neurology. _Nat Med_ 1, 1247–1248 (1995). https://doi.org/10.1038/nm1295-1247 Download citation * Issue Date: 01 December 1995 * DOI: https://doi.org/10.1038/nm1295-1247 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

Computer simulations of theoretical models provide a way to elucidate mechanisms underlying neurological disorders and drug actions. Access through your institution Buy or subscribe This is


a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per


year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated


during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support REFERENCES * Hodgkin, A.L. & Huxley, A.F. A


quantitative description of membrane current and its application to conduction and excitation in nerve. _J. Physiol Lond._ 117, 500–544 (1952). Article  CAS  Google Scholar  * Cannon, S.C.


& Corey, D.P. Loss of sodium channel inactivation by anemone toxin (ATX II) mimics the myotonic state in hyperkaliemic periodic paralysis. _J. Physiol._ 466, 501–520 (1993). CAS  PubMed


  PubMed Central  Google Scholar  * Cannon, S.C., Brown, R.H. & Corey, D. Theoretical reconstruction of myotonia and paralysis caused by incomplete inactivation of sodium channels.


_Biophys. J._ 65, 270–288 (1993). Article  CAS  Google Scholar  * Lytton, W.W. & Sejnowski, T.J. Computer model of ethosuximide's effect on a thalamic neuron. _Ann. Neurol._ 32,


131–139 (1992). Article  CAS  Google Scholar  * Vibert, J.-F., Pham, J., Pakdaman, K. & Azmy, N. XNBC: A simulation tool for neurobiologists. in _The Neurobiology of Computation_ (ed.


Bower, J.) 346–352 (Kluwer Academic Pub., Boston, 1995). Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Faculté de Médecine Saint–Antoine, Université


Pierre et Marie–Curie, 75571, Paris Cedex, 12, France Jean-Francois Vibert, Khashayar Pakdaman, Eric Boussard & Evyatar Av-Ron Authors * Jean-Francois Vibert View author publications You


can also search for this author inPubMed Google Scholar * Khashayar Pakdaman View author publications You can also search for this author inPubMed Google Scholar * Eric Boussard View author


publications You can also search for this author inPubMed Google Scholar * Evyatar Av-Ron View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND


PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Vibert, JF., Pakdaman, K., Boussard, E. _et al._ Computational neuroscience and neurology. _Nat Med_ 1, 1247–1248


(1995). https://doi.org/10.1038/nm1295-1247 Download citation * Issue Date: 01 December 1995 * DOI: https://doi.org/10.1038/nm1295-1247 SHARE THIS ARTICLE Anyone you share the following link


with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt


content-sharing initiative