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Access through your institution Buy or subscribe EFFICIENT TRANSGENESIS IN FARM ANIMALS BY LENTIVIRAL VECTORS. Hofmann, A. _et al_. _EMBO Rep._ 4, 1054–1060 (2003) Hofmann _et al_. infected
single-cell pig embryos with recombinant lentiviral vector that carried a ubiquitously active promoter and a green fluorescent protein (GFP) reporter transgene. Of the piglets born, 65%
expressed the transgene. GFP was detected in all tissues, including germ cells, and the transgene was transmitted through the germline. This first successful application of lentiviral
vectors to livestock promises to reduce the cost of producing transgenic farm animals. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through
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https://doi.org/10.1038/nrg1243 Download citation * Issue Date: December 2003 * DOI: https://doi.org/10.1038/nrg1243 SHARE THIS ARTICLE Anyone you share the following link with will be able
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