Il-1 trap prevents and treats gouty arthritis in a new mouse model

Il-1 trap prevents and treats gouty arthritis in a new mouse model

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Access through your institution Buy or subscribe Torres, R. _ et al_. Hyperalgesia, synovitis, and multiple biomarkers of inflammation are suppressed by IL–1 inhibition in a novel animal model of gouty arthritis. _Ann. Rheum. Dis._ doi:10.1136/ard.2009.109355 Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap) could be an effective therapy for the pain and inflammation associated with acute gout. As demonstrated in a novel mouse model, the mouse version of the drug (mIL-1 Trap) both prevented and relieved ankle joint synovitis and hyperalgesia induced by monosodium urate (MSU) crystals. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support Authors * Sarah Price View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Price, S. IL-1 Trap prevents and treats gouty arthritis in a new mouse model. _Nat Rev Rheumatol_ 5, 466 (2009). https://doi.org/10.1038/nrrheum.2009.156 Download citation * Issue Date: September 2009 * DOI: https://doi.org/10.1038/nrrheum.2009.156 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

Access through your institution Buy or subscribe Torres, R. _ et al_. Hyperalgesia, synovitis, and multiple biomarkers of inflammation are suppressed by IL–1 inhibition in a novel animal


model of gouty arthritis. _Ann. Rheum. Dis._ doi:10.1136/ard.2009.109355 Systemic inhibition of interleukin (IL)-1 with rilonacept (IL-1 Trap) could be an effective therapy for the pain and


inflammation associated with acute gout. As demonstrated in a novel mouse model, the mouse version of the drug (mIL-1 Trap) both prevented and relieved ankle joint synovitis and hyperalgesia


induced by monosodium urate (MSU) crystals. This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal


Receive 12 print issues and online access $209.00 per year only $17.42 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices


may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support


Authors * Sarah Price View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS


ARTICLE Price, S. IL-1 Trap prevents and treats gouty arthritis in a new mouse model. _Nat Rev Rheumatol_ 5, 466 (2009). https://doi.org/10.1038/nrrheum.2009.156 Download citation * Issue


Date: September 2009 * DOI: https://doi.org/10.1038/nrrheum.2009.156 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry,


a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative