Classical PUF proteins bind to single-stranded RNA with sequence specificity that can be engineered by site-directed mutagenesis according to a simple RNA-recognition code. Now in-depth

probing of the PUF RNA-recognition code enhances future design of PUF proteins and exposes hidden complexity in generating specificity. Access through your institution Buy or subscribe This

is a preview of subscription content, access via your institution RELEVANT ARTICLES Open Access articles citing this article. * EXPANDING THE BINDING SPECIFICITY FOR RNA RECOGNITION BY A PUF

DOMAIN * Wei Zhou * , Daniel Melamed *  … Stanley Fields _Nature Communications_ Open Access 24 August 2021 * STRUCTURE ALIGNMENT-BASED CLASSIFICATION OF RNA-BINDING POCKETS REVEALS

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our FAQs * Contact customer support ACCESSION CODES ACCESSIONS PROTEIN DATA BANK * 3V6Y REFERENCES * Wharton, R.P. & Aggarwal, A.K. _Sci. STKE_ 2006, pe37 (2006). Article  Google Scholar

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AFFILIATIONS * Traci M. Tanaka Hall is at the Laboratory of Structural Biology, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park,

North Carolina, USA., Traci M Tanaka Hall Authors * Traci M Tanaka Hall View author publications You can also search for this author inPubMed Google Scholar CORRESPONDING AUTHOR

Correspondence to Traci M Tanaka Hall. ETHICS DECLARATIONS COMPETING INTERESTS The author declares no competing financial interests. RIGHTS AND PERMISSIONS Reprints and permissions ABOUT

THIS ARTICLE CITE THIS ARTICLE Hall, T. Expanding the RNA-recognition code of PUF proteins. _Nat Struct Mol Biol_ 21, 653–655 (2014). https://doi.org/10.1038/nsmb.2863 Download citation *

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