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ABSTRACT From July 1976 to Dec. 1979, 300 premature infants, weighing between 1000 and 2300 gm were studied for the incidence of infection in relation to duration of ROM. They were divided
into 6 groups of infants with 0-15/60, 16/60-23, 24-71 and greater than 72 hours of ROM. There were 82, 127, 51 and 40 infants in each group respectively. The incidence of proven infection
was 8% (24) out of which 5% (15) had positive blood culture, 3% (4) had meningitis and 3.3% (10) had urinary tract infection. The incidence of clinical sepsis was 33.3% (100). The incidence
of clinical and proven sepsis was not related to the duration of ROM. The incidence of antibiotic therapy was significantly related to the duration of ROM particularly in infants more than
32 weeks and 1500 gm. When they were small and extremely immature, 2/3 of them were on antibiotic therapy and it was not related to the duration of ROM. As the duration of ROM increases, the
incidence of amnionitis and maternal antibiotic therapy increased only when the infants were greater than 32 weeks and 1500 gm. There were no correlations between the duration of ROM and
the incidence of meconium stained amniotic fluid, fetal distress and severe perinatal asphyxia. Infants 32 weeks or less with greater than 72 hours of ROM had the lowest incidence of severe
perinatal asphyxia. The mortality rate was not related to the duration of ROM. However, when there was no associated proven infection, significantly higher mortality was noted in infants
with greater than 24 hrs. of ROM which was often associated with severe perinatal asphyxia. This study revealed that the duration of ROM did not seem to effect the incidence of infection,
fetal distress, perinatal asphyxia and mortality in premature infants. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Albert Einstein Coll. of Med., Bronx-Lebanon Hosp. Ctr.,
Dept. of Ped. and Obst., Bronx, NY. J J Yoon, A E Esquea, J N Rao, M N Wijesinghe & M Cohen Authors * J J Yoon View author publications You can also search for this author inPubMed
Google Scholar * A E Esquea View author publications You can also search for this author inPubMed Google Scholar * J N Rao View author publications You can also search for this author
inPubMed Google Scholar * M N Wijesinghe View author publications You can also search for this author inPubMed Google Scholar * M Cohen View author publications You can also search for this
author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Yoon, J., Esquea, A., Rao, J. _et al._ 1093 INCIDENCE OF INFECTION IN
RELATION TO DURATION OF RUPTURE OF MEMBRANES (ROM) IN PREMATURE INFANTS. _Pediatr Res_ 15 (Suppl 4), 625 (1981). https://doi.org/10.1203/00006450-198104001-01119 Download citation * Issue
Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01119 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link
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