1335 prediction of retrolental fibroplasia (rlf)

1335 prediction of retrolental fibroplasia (rlf)

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ABSTRACT Incidence and severity of RLF was defined by a standard grading system in 269 premature infants with birth weight (BW)≤2000 gm or gestational age (GA) ≤36 weeks and needing oxygen (O2) therapy Prediction of mean severity of RLF (acute stage, all babies) was studied by a multiple regression equation which reports proportion of total outcome variance (cumulative R Square) accounted for by the predictor variables available. It selects independent variables in order of additional contribution to RSq, the best predictor being selected first. Very weak predictors do not enter the equation. The last RSq in the summary table represents the total variance accounted for by all risk factors considered and amounts to only 35.8%.From a clinical standpoint, only BW (or GA) is a major predictor. Carefully controlled O2 Rx seems to pose only a small risk. As yet undefined differences, probably largely genetic, (Phelp's queen effect), are of major importance. The Dependent Variable is Mean Severity of RLF for All Infants ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Univ. of Penn. Sch. Med, Lois H Johnson, David B Schaffer, Donald Goldstein, Mari Jo Mathis & Thomas R Boggs * Penn. Hosp., Dept. Peds, Lois H Johnson, David B Schaffer, Donald Goldstein, Mari Jo Mathis & Thomas R Boggs * Children's Hosp., Dept. Ophthal., Phila., Pa. Lois H Johnson, David B Schaffer, Donald Goldstein, Mari Jo Mathis & Thomas R Boggs Authors * Lois H Johnson View author publications You can also search for this author inPubMed Google Scholar * David B Schaffer View author publications You can also search for this author inPubMed Google Scholar * Donald Goldstein View author publications You can also search for this author inPubMed Google Scholar * Mari Jo Mathis View author publications You can also search for this author inPubMed Google Scholar * Thomas R Boggs View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Johnson, L., Schaffer, D., Goldstein, D. _et al._ 1335 PREDICTION OF RETROLENTAL FIBROPLASIA (RLF). _Pediatr Res_ 15 (Suppl 4), 665 (1981). https://doi.org/10.1203/00006450-198104001-01364 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01364 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT Incidence and severity of RLF was defined by a standard grading system in 269 premature infants with birth weight (BW)≤2000 gm or gestational age (GA) ≤36 weeks and needing oxygen


(O2) therapy Prediction of mean severity of RLF (acute stage, all babies) was studied by a multiple regression equation which reports proportion of total outcome variance (cumulative R


Square) accounted for by the predictor variables available. It selects independent variables in order of additional contribution to RSq, the best predictor being selected first. Very weak


predictors do not enter the equation. The last RSq in the summary table represents the total variance accounted for by all risk factors considered and amounts to only 35.8%.From a clinical


standpoint, only BW (or GA) is a major predictor. Carefully controlled O2 Rx seems to pose only a small risk. As yet undefined differences, probably largely genetic, (Phelp's queen


effect), are of major importance. The Dependent Variable is Mean Severity of RLF for All Infants ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Univ. of Penn. Sch. Med, Lois H


Johnson, David B Schaffer, Donald Goldstein, Mari Jo Mathis & Thomas R Boggs * Penn. Hosp., Dept. Peds, Lois H Johnson, David B Schaffer, Donald Goldstein, Mari Jo Mathis & Thomas R


Boggs * Children's Hosp., Dept. Ophthal., Phila., Pa. Lois H Johnson, David B Schaffer, Donald Goldstein, Mari Jo Mathis & Thomas R Boggs Authors * Lois H Johnson View author


publications You can also search for this author inPubMed Google Scholar * David B Schaffer View author publications You can also search for this author inPubMed Google Scholar * Donald


Goldstein View author publications You can also search for this author inPubMed Google Scholar * Mari Jo Mathis View author publications You can also search for this author inPubMed Google


Scholar * Thomas R Boggs View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS


ARTICLE Johnson, L., Schaffer, D., Goldstein, D. _et al._ 1335 PREDICTION OF RETROLENTAL FIBROPLASIA (RLF). _Pediatr Res_ 15 (Suppl 4), 665 (1981).


https://doi.org/10.1203/00006450-198104001-01364 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01364 SHARE THIS ARTICLE Anyone you share the


following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer


Nature SharedIt content-sharing initiative