1451 intrauterine fetal resuscitation with terbutaline

1451 intrauterine fetal resuscitation with terbutaline

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ABSTRACT Cases of intrapartal fetal distress from any cause sustain further hypoxia during uterine contractions due to the concomitant reduction in uterine blood flow during uterine activity. Therapeutic reduction of uterine activity should, therefore, result in recovery of fetal heart rate (FHR) and fetal acidosis, and the birth of a neonate in a better state of oxygenation and acid-base balance. Towards this, terbutaline 250 μg subcutaneously was injected in patients with evidence of fetal distress. All 11 patients showed ominous FHR changes. In 2 of these,fetal scalp blood pH (FSB-pH) was not technically possible. In 2, the FSB-pH was > 7.25. The remaining 7 patients showed FSB-pH ≥ 7.25. Results: Where adequate FHR trace was available, 9/10 patients showed marked reduction to cessation of uterine activity, and complete or partial recovery of ominous FHR changes. FSB-pH was compared to the mid-point of the umbilical vein and artery pH's. In the 2 cases where the original FSB-pH was > 7.25, no change was seen. However, in cases with FSB-pH ≥ 7.25, a significant improvement from a mean of 7.180 ± .038 to 7.270 ± .066 (P = <.005) was seen. No major side effects were noted. It is concluded that in addition to conventional management of fetal distress, tocolysis with terbutaline can improve the status of a distressed fetus and result in the birth of a healthy neonate. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Spon. by Platon J. Collipp. Nassau Cty Med Ctr, Hlth Sci Ctr, SUNY at Stony Brook, Dept. of Ob/Gyn, East Meadow, NY Nergesh A Tejani, Uma L Verma & Syamali Chatterjee Authors * Nergesh A Tejani View author publications You can also search for this author inPubMed Google Scholar * Uma L Verma View author publications You can also search for this author inPubMed Google Scholar * Syamali Chatterjee View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Tejani, N., Verma, U. & Chatterjee, S. 1451 INTRAUTERINE FETAL RESUSCITATION WITH TERBUTALINE. _Pediatr Res_ 15 (Suppl 4), 685 (1981). https://doi.org/10.1203/00006450-198104001-01480 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01480 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT Cases of intrapartal fetal distress from any cause sustain further hypoxia during uterine contractions due to the concomitant reduction in uterine blood flow during uterine


activity. Therapeutic reduction of uterine activity should, therefore, result in recovery of fetal heart rate (FHR) and fetal acidosis, and the birth of a neonate in a better state of


oxygenation and acid-base balance. Towards this, terbutaline 250 μg subcutaneously was injected in patients with evidence of fetal distress. All 11 patients showed ominous FHR changes. In 2


of these,fetal scalp blood pH (FSB-pH) was not technically possible. In 2, the FSB-pH was > 7.25. The remaining 7 patients showed FSB-pH ≥ 7.25. Results: Where adequate FHR trace was


available, 9/10 patients showed marked reduction to cessation of uterine activity, and complete or partial recovery of ominous FHR changes. FSB-pH was compared to the mid-point of the


umbilical vein and artery pH's. In the 2 cases where the original FSB-pH was > 7.25, no change was seen. However, in cases with FSB-pH ≥ 7.25, a significant improvement from a mean


of 7.180 ± .038 to 7.270 ± .066 (P = <.005) was seen. No major side effects were noted. It is concluded that in addition to conventional management of fetal distress, tocolysis with


terbutaline can improve the status of a distressed fetus and result in the birth of a healthy neonate. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Spon. by Platon J. Collipp.


Nassau Cty Med Ctr, Hlth Sci Ctr, SUNY at Stony Brook, Dept. of Ob/Gyn, East Meadow, NY Nergesh A Tejani, Uma L Verma & Syamali Chatterjee Authors * Nergesh A Tejani View author


publications You can also search for this author inPubMed Google Scholar * Uma L Verma View author publications You can also search for this author inPubMed Google Scholar * Syamali


Chatterjee View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Tejani,


N., Verma, U. & Chatterjee, S. 1451 INTRAUTERINE FETAL RESUSCITATION WITH TERBUTALINE. _Pediatr Res_ 15 (Suppl 4), 685 (1981). https://doi.org/10.1203/00006450-198104001-01480 Download


citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-01480 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content:


Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative