651 growth & development of infants < 1500 g fed banked human milk (bhm) or premature formula (f)

651 growth & development of infants < 1500 g fed banked human milk (bhm) or premature formula (f)

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ABSTRACT BHM composition and nutritional adequacy for infants < 1500g has not been established. We have randomized 65 infants < 1500g to ad lib feeds of F (Similae Special Care, a protein and mineral enriched formula designed to sustain intrauterine-like growth) or frozen BHM until infants weighed 2000g. BHM was low in fat (2.3%) and calories (bomb analysis 58 cal/100g), a finding also recently noted by Carroll. BHM infants ingested more milk (192 vs 162 ml/kg/d) but fewer calories (121 vs 142 cal/kg/d); grew less in weight (14 vs 30 g/d), length (0.7 vs 1.1 cm/wk), and FOC (0.8 vs 1.2 cm/wk); and at 37 wks post-conception were less responsive to visual & auditory stimuli (Brazelton orientation items, mean score = 2.4 vs 3.6; p < 0.05). Amino acids, BUN, and pH values were similar. Findings at blind evaluation 92 wks post-conception: Bayley developmental scores were higher for F than BHM infants at 92 wks (PDI:92 vs 78; p<0.05; MDI:89 vs 76, p=0.13). Birthweight, gest. age, and need for ventilation were similar for BHM and F infants seen at 92 wks. F supports near intrauterine growth rates and may confer short and long term advantages over BHM for infants < 1500g. *Actual age minus age at which measurements equal 50th percentile. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * U. Tex. Health Sci. Cntr. at Dallas, Dept. Peds., J Tyson, R Lasky, C Mize, R White & C Fink Authors * J Tyson View author publications You can also search for this author inPubMed Google Scholar * R Lasky View author publications You can also search for this author inPubMed Google Scholar * C Mize View author publications You can also search for this author inPubMed Google Scholar * R White View author publications You can also search for this author inPubMed Google Scholar * C Fink View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Tyson, J., Lasky, R., Mize, C. _et al._ 651 GROWTH & DEVELOPMENT OF INFANTS < 1500 g FED BANKED HUMAN MILK (BHM) OR PREMATURE FORMULA (F). _Pediatr Res_ 15 (Suppl 4), 549 (1981). https://doi.org/10.1203/00006450-198104001-00664 Download citation * Issue Date: 01 April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-00664 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT BHM composition and nutritional adequacy for infants < 1500g has not been established. We have randomized 65 infants < 1500g to ad lib feeds of F (Similae Special Care, a


protein and mineral enriched formula designed to sustain intrauterine-like growth) or frozen BHM until infants weighed 2000g. BHM was low in fat (2.3%) and calories (bomb analysis 58


cal/100g), a finding also recently noted by Carroll. BHM infants ingested more milk (192 vs 162 ml/kg/d) but fewer calories (121 vs 142 cal/kg/d); grew less in weight (14 vs 30 g/d), length


(0.7 vs 1.1 cm/wk), and FOC (0.8 vs 1.2 cm/wk); and at 37 wks post-conception were less responsive to visual & auditory stimuli (Brazelton orientation items, mean score = 2.4 vs 3.6; p


< 0.05). Amino acids, BUN, and pH values were similar. Findings at blind evaluation 92 wks post-conception: Bayley developmental scores were higher for F than BHM infants at 92 wks


(PDI:92 vs 78; p<0.05; MDI:89 vs 76, p=0.13). Birthweight, gest. age, and need for ventilation were similar for BHM and F infants seen at 92 wks. F supports near intrauterine growth rates


and may confer short and long term advantages over BHM for infants < 1500g. *Actual age minus age at which measurements equal 50th percentile. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND


AFFILIATIONS * U. Tex. Health Sci. Cntr. at Dallas, Dept. Peds., J Tyson, R Lasky, C Mize, R White & C Fink Authors * J Tyson View author publications You can also search for this author


inPubMed Google Scholar * R Lasky View author publications You can also search for this author inPubMed Google Scholar * C Mize View author publications You can also search for this author


inPubMed Google Scholar * R White View author publications You can also search for this author inPubMed Google Scholar * C Fink View author publications You can also search for this author


inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Tyson, J., Lasky, R., Mize, C. _et al._ 651 GROWTH & DEVELOPMENT OF INFANTS


< 1500 g FED BANKED HUMAN MILK (BHM) OR PREMATURE FORMULA (F). _Pediatr Res_ 15 (Suppl 4), 549 (1981). https://doi.org/10.1203/00006450-198104001-00664 Download citation * Issue Date: 01


April 1981 * DOI: https://doi.org/10.1203/00006450-198104001-00664 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a


shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative