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ABSTRACT The fat composition of special formula milk for VLBW infants may include up to 50% MCT. During feeding with two formulas (Nutricia, Holland) containing per 100 ml: 80 kcal, 8.0 g
carbohydr., 2.2 g protein and 4.4 g fat with 40% MCT (A) or 5% MCT (B), glucose oxidation was measured by primed constant oral infusion of U-13C glucose as 13CO2 recovery in breath and
substrate utilization by indirect calorimetry. At week 4, 15 infants (birthw.1236±228 g, gest.age 32.0±2.2 wks) received 150 ml/kg/day of formula A and 10 infants (birthw.1304±165 g,
gest.age.32.6±1.9wks) received B. Net fat oxid. was calculated as non-protein met.rate - net gluc.oxid. Results in g/kg/d or kcal/kg/d ±S.D.: Conclusions: 1. No differences were found in
net.rate and substrate util of infants fed formula A or B. 2. However, increasing the % MCT causes a significant decrease in net glucose oxid as measured with stable isotopes. 3. Combining
these methods we also conclude that net fat oxidation is higher in the high MCT group. ARTICLE PDF AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Dept. of Pediatrics, Erasmus University
Rotterdam, Sophia Children's Hosp., Rotterdam, The Netherlands Eric J Sulkers, Harry N Lafeber & Pieter J J Sauer Authors * Eric J Sulkers View author publications You can also
search for this author inPubMed Google Scholar * Harry N Lafeber View author publications You can also search for this author inPubMed Google Scholar * Pieter J J Sauer View author
publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Sulkers, E., Lafeber, H. &
Sauer, P. GLUCOSE OXIDATION AND SUBSTRATE UTILIZATION IN VLBW INFANTS FED A FORMULA CONTAINING 5 OR 40 PERCENT OF FAT AS MEDIUM CHAIN TRIGLYCERIDES (MCT). _Pediatr Res_ 26, 514 (1989).
https://doi.org/10.1203/00006450-198911000-00088 Download citation * Issue Date: 01 November 1989 * DOI: https://doi.org/10.1203/00006450-198911000-00088 SHARE THIS ARTICLE Anyone you share
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