The Enzyme Electrode | Nature

The Enzyme Electrode | Nature

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ABSTRACT The enzyme electrode is a miniature chemical transducer which functions by combining an electrochemical procedure with immobilized enzyme activity. This particular model uses glucose oxidase immobilized on a gel to measure the concentration of glucose in biological solutions and in the tissues _in vitro_. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS DEVICE INTEGRATION OF ELECTROCHEMICAL BIOSENSORS Article 24 February 2023 BIOMOLECULE SENSORS BASED ON ORGANIC ELECTROCHEMICAL TRANSISTORS Article Open access 13 February 2025 CREATION OF A POINT-OF-CARE THERAPEUTICS SENSOR USING PROTEIN ENGINEERING, ELECTROCHEMICAL SENSING AND ELECTRONIC INTEGRATION Article Open access 24 February 2024 REFERENCES * Caceres, C. A., _Biomedical Telemetry_ (Academic Press, New York and London, 1965). Google Scholar  * Meyer, M. S., Gotch, F., and Tazaki, _J. App. Physiol._, 16, 896 (1961). Article  CAS  Google Scholar  * Gotch, F., Meyer, J. S., and Ebihara, S., _Med. Eng. Res._, 5, 13 (1966). Google Scholar  * Steinberg, W. H., Mina, F. A., Pick, P. G., and Frey, G. H., _J. Pharm. Sci._, 54, 772 (1965). Article  CAS  Google Scholar  * Clark, L. C., _Trans. Amer. Soc. Artif. Intern. Organs_, 2, 41 (1956). Google Scholar  * Hicks, G. P., and Updike, S. J., _Anal. Chem._, 38, 726 (1966). Article  CAS  Google Scholar  * Charlton, G., Read, D., and Read, J., _J. App. Physiol._, 18, 1247 (1963). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Medicine, University of Wisconsin, Madison, Wisconsin S. J. UPDIKE & G. P. HICKS Authors * S. J. UPDIKE View author publications You can also search for this author inPubMed Google Scholar * G. P. HICKS View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE UPDIKE, S., HICKS, G. The Enzyme Electrode. _Nature_ 214, 986–988 (1967). https://doi.org/10.1038/214986a0 Download citation * Received: 20 February 1967 * Published: 01 June 1967 * Issue Date: 03 June 1967 * DOI: https://doi.org/10.1038/214986a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT The enzyme electrode is a miniature chemical transducer which functions by combining an electrochemical procedure with immobilized enzyme activity. This particular model uses


glucose oxidase immobilized on a gel to measure the concentration of glucose in biological solutions and in the tissues _in vitro_. Access through your institution Buy or subscribe This is a


preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per


year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during


checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS DEVICE INTEGRATION


OF ELECTROCHEMICAL BIOSENSORS Article 24 February 2023 BIOMOLECULE SENSORS BASED ON ORGANIC ELECTROCHEMICAL TRANSISTORS Article Open access 13 February 2025 CREATION OF A POINT-OF-CARE


THERAPEUTICS SENSOR USING PROTEIN ENGINEERING, ELECTROCHEMICAL SENSING AND ELECTRONIC INTEGRATION Article Open access 24 February 2024 REFERENCES * Caceres, C. A., _Biomedical Telemetry_


(Academic Press, New York and London, 1965). Google Scholar  * Meyer, M. S., Gotch, F., and Tazaki, _J. App. Physiol._, 16, 896 (1961). Article  CAS  Google Scholar  * Gotch, F., Meyer, J.


S., and Ebihara, S., _Med. Eng. Res._, 5, 13 (1966). Google Scholar  * Steinberg, W. H., Mina, F. A., Pick, P. G., and Frey, G. H., _J. Pharm. Sci._, 54, 772 (1965). Article  CAS  Google


Scholar  * Clark, L. C., _Trans. Amer. Soc. Artif. Intern. Organs_, 2, 41 (1956). Google Scholar  * Hicks, G. P., and Updike, S. J., _Anal. Chem._, 38, 726 (1966). Article  CAS  Google


Scholar  * Charlton, G., Read, D., and Read, J., _J. App. Physiol._, 18, 1247 (1963). Article  CAS  Google Scholar  Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS *


Department of Medicine, University of Wisconsin, Madison, Wisconsin S. J. UPDIKE & G. P. HICKS Authors * S. J. UPDIKE View author publications You can also search for this author


inPubMed Google Scholar * G. P. HICKS View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE


CITE THIS ARTICLE UPDIKE, S., HICKS, G. The Enzyme Electrode. _Nature_ 214, 986–988 (1967). https://doi.org/10.1038/214986a0 Download citation * Received: 20 February 1967 * Published: 01


June 1967 * Issue Date: 03 June 1967 * DOI: https://doi.org/10.1038/214986a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link


Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative