Direction of transcription of a regulatory gene in e. Coli

Direction of transcription of a regulatory gene in e. Coli

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ABSTRACT The _i_ gene, which codes for the _lac_ repressor, is transcribed in the same direction as the structural genes (_z, y, a_) of the _lac_ operon. Access through your institution Buy or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY OTHERS REDEFINING FUNDAMENTAL CONCEPTS OF TRANSCRIPTION INITIATION IN BACTERIA Article 14 July 2020 GENERAL TRANSCRIPTION FACTOR FROM _ESCHERICHIA COLI_ WITH A DISTINCT MECHANISM OF ACTION Article Open access 04 January 2024 WIDESPREAD DIVERGENT TRANSCRIPTION FROM BACTERIAL AND ARCHAEAL PROMOTERS IS A CONSEQUENCE OF DNA-SEQUENCE SYMMETRY Article 06 May 2021 REFERENCES * Jacob, F., and Monod, J., _J. Mol. Biol._, 3, 318 (1961). Article  CAS  PubMed  Google Scholar  * Gilbert, W., and Muller-Hill, B., _Proc. US Nat. Acad. Sci._, 56, 1891 (1966). Article  ADS  CAS  Google Scholar  * Gilbert, W., and Muller-Hill, B., _Proc. US Nat. Acad. Sci._, 58, 2415 (1967). Article  ADS  CAS  Google Scholar  * Ippen, K., Miller, J. H., Scaife, J. G., and Beckwith, J. R., _Nature_, 217, 825 (1968). Article  ADS  CAS  PubMed  Google Scholar  * Epstein, W., and Beckwith, J. R., _Ann. Rev. Biochem._, 37, 411 (1968). Article  CAS  Google Scholar  * Beckwith, J. R., Signer, E. R., and Epstein, W., _Cold Spring Harbor Symp. Quant. Biol._, 31, 393 (1966). Article  CAS  PubMed  Google Scholar  * Sanderson, K. E., and Demerec, M., _Genetics_, 51, 897 (1965). PubMed  PubMed Central  CAS  Google Scholar  * Miller, J. H., Ippen, K., Scaife, J. G., and Beckwith, J. R., _J. Mol. Biol._, 38 (1968). * Muller-Hill, B., Gilbert, W., and Crapo, L., _Proc. US Nat. Acad. Sci._, 59, 1259 (1968). Article  ADS  CAS  Google Scholar  * Davies, J., and Jacob, F., _J. Mol. Biol._, 36, 413 (1968). Article  CAS  PubMed  Google Scholar  * Sadler, J. R., and Novick, A., _J. Mol. Biol._, 12, 305 (1965). Article  CAS  PubMed  Google Scholar  * Sarabhai, A., and Brenner, S., _J. Mol. Biol._, 27, 145 (1968). Article  Google Scholar  * Scaife, J. G., and Beckwith, J. R., _Cold Spring Harbor Symp. Quant. Biol._, 31, 403 (1966). Article  CAS  PubMed  Google Scholar  * Newton, W. A., Beckwith, J. R., Zipser, D., and Brenner, S., _J. Mol. Biol._, 14, 290 (1965). Article  CAS  PubMed  Google Scholar  * Kumar, S., and Szybalski, W., _J. Mol. Biol._ (in the press). Download references AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Bacteriology and Immunology, Harvard Medical School, Boston, Massachusetts JEFFREY H. MILLER & JON BECKWITH * Institute of Genetics, University of Cologne, BENNO MULLER-HILL Authors * JEFFREY H. MILLER View author publications You can also search for this author inPubMed Google Scholar * JON BECKWITH View author publications You can also search for this author inPubMed Google Scholar * BENNO MULLER-HILL View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE MILLER, J., BECKWITH, J. & MULLER-HILL, B. Direction of Transcription of a Regulatory Gene in _E. coli_. _Nature_ 220, 1287–1290 (1968). https://doi.org/10.1038/2201287a0 Download citation * Received: 12 December 1968 * Issue Date: 28 December 1968 * DOI: https://doi.org/10.1038/2201287a0 SHARE THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to clipboard Provided by the Springer Nature SharedIt content-sharing initiative

ABSTRACT The _i_ gene, which codes for the _lac_ repressor, is transcribed in the same direction as the structural genes (_z, y, a_) of the _lac_ operon. Access through your institution Buy


or subscribe This is a preview of subscription content, access via your institution ACCESS OPTIONS Access through your institution Subscribe to this journal Receive 51 print issues and


online access $199.00 per year only $3.90 per issue Learn more Buy this article * Purchase on SpringerLink * Instant access to full article PDF Buy now Prices may be subject to local taxes


which are calculated during checkout ADDITIONAL ACCESS OPTIONS: * Log in * Learn about institutional subscriptions * Read our FAQs * Contact customer support SIMILAR CONTENT BEING VIEWED BY


OTHERS REDEFINING FUNDAMENTAL CONCEPTS OF TRANSCRIPTION INITIATION IN BACTERIA Article 14 July 2020 GENERAL TRANSCRIPTION FACTOR FROM _ESCHERICHIA COLI_ WITH A DISTINCT MECHANISM OF ACTION


Article Open access 04 January 2024 WIDESPREAD DIVERGENT TRANSCRIPTION FROM BACTERIAL AND ARCHAEAL PROMOTERS IS A CONSEQUENCE OF DNA-SEQUENCE SYMMETRY Article 06 May 2021 REFERENCES * Jacob,


F., and Monod, J., _J. Mol. Biol._, 3, 318 (1961). Article  CAS  PubMed  Google Scholar  * Gilbert, W., and Muller-Hill, B., _Proc. US Nat. Acad. Sci._, 56, 1891 (1966). Article  ADS  CAS 


Google Scholar  * Gilbert, W., and Muller-Hill, B., _Proc. US Nat. Acad. Sci._, 58, 2415 (1967). Article  ADS  CAS  Google Scholar  * Ippen, K., Miller, J. H., Scaife, J. G., and Beckwith,


J. R., _Nature_, 217, 825 (1968). Article  ADS  CAS  PubMed  Google Scholar  * Epstein, W., and Beckwith, J. R., _Ann. Rev. Biochem._, 37, 411 (1968). Article  CAS  Google Scholar  *


Beckwith, J. R., Signer, E. R., and Epstein, W., _Cold Spring Harbor Symp. Quant. Biol._, 31, 393 (1966). Article  CAS  PubMed  Google Scholar  * Sanderson, K. E., and Demerec, M.,


_Genetics_, 51, 897 (1965). PubMed  PubMed Central  CAS  Google Scholar  * Miller, J. H., Ippen, K., Scaife, J. G., and Beckwith, J. R., _J. Mol. Biol._, 38 (1968). * Muller-Hill, B.,


Gilbert, W., and Crapo, L., _Proc. US Nat. Acad. Sci._, 59, 1259 (1968). Article  ADS  CAS  Google Scholar  * Davies, J., and Jacob, F., _J. Mol. Biol._, 36, 413 (1968). Article  CAS  PubMed


  Google Scholar  * Sadler, J. R., and Novick, A., _J. Mol. Biol._, 12, 305 (1965). Article  CAS  PubMed  Google Scholar  * Sarabhai, A., and Brenner, S., _J. Mol. Biol._, 27, 145 (1968).


Article  Google Scholar  * Scaife, J. G., and Beckwith, J. R., _Cold Spring Harbor Symp. Quant. Biol._, 31, 403 (1966). Article  CAS  PubMed  Google Scholar  * Newton, W. A., Beckwith, J.


R., Zipser, D., and Brenner, S., _J. Mol. Biol._, 14, 290 (1965). Article  CAS  PubMed  Google Scholar  * Kumar, S., and Szybalski, W., _J. Mol. Biol._ (in the press). Download references


AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Department of Bacteriology and Immunology, Harvard Medical School, Boston, Massachusetts JEFFREY H. MILLER & JON BECKWITH * Institute of


Genetics, University of Cologne, BENNO MULLER-HILL Authors * JEFFREY H. MILLER View author publications You can also search for this author inPubMed Google Scholar * JON BECKWITH View author


publications You can also search for this author inPubMed Google Scholar * BENNO MULLER-HILL View author publications You can also search for this author inPubMed Google Scholar RIGHTS AND


PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE MILLER, J., BECKWITH, J. & MULLER-HILL, B. Direction of Transcription of a Regulatory Gene in _E. coli_.


_Nature_ 220, 1287–1290 (1968). https://doi.org/10.1038/2201287a0 Download citation * Received: 12 December 1968 * Issue Date: 28 December 1968 * DOI: https://doi.org/10.1038/2201287a0 SHARE


THIS ARTICLE Anyone you share the following link with will be able to read this content: Get shareable link Sorry, a shareable link is not currently available for this article. Copy to


clipboard Provided by the Springer Nature SharedIt content-sharing initiative