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ABSTRACT The lymphoid system is known to be involved in the propagation and spread of scrapie. However, the identity of the cell type responsible for scrapie replication remains
controversial. A new study provides evidence that the follicular dendritic cells in the spleen are the targets of this infectious form of prion (pages 1308–1312). Access through your
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AUTHOR INFORMATION AUTHORS AND AFFILIATIONS * Division of Neuropathology Institute of Pathology Case Western Reserve University School of Medicine, 10900 Euclid Ave., Cleveland, 44106-4943,
OH Man-Sun Sy & Pierluigi Gambetti Authors * Man-Sun Sy View author publications You can also search for this author inPubMed Google Scholar * Pierluigi Gambetti View author publications
You can also search for this author inPubMed Google Scholar RIGHTS AND PERMISSIONS Reprints and permissions ABOUT THIS ARTICLE CITE THIS ARTICLE Sy, MS., Gambetti, P. Prion replication—once
again blaming the dendritic cell. _Nat Med_ 5, 1235–1237 (1999). https://doi.org/10.1038/15186 Download citation * Issue Date: November 1999 * DOI: https://doi.org/10.1038/15186 SHARE THIS
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